Changes between Version 25 and Version 26 of barOpossumSupplement


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Timestamp:
11/07/16 09:49:54 (7 years ago)
Author:
pmajka
Comment:

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  • barOpossumSupplement

    v25 v26  
    99= ABSTRACT = 
    1010 
    11  The gray short-tailed opossum (''Monodelphis domestica'') is a small marsupial gaining recognition as a laboratory animal in biomedical research. Despite numerous studies on opossum neuroanatomy, a consistent and comprehensive neuroanatomical reference for this species is still missing. 
     11The gray short-tailed opossum (''Monodelphis domestica'') is a small marsupial gaining recognition as a laboratory animal in biomedical research. Despite numerous studies on opossum neuroanatomy, a consistent and comprehensive neuroanatomical reference for this species is still missing. 
    1212 
    13  Here we present the first three-dimensional, multimodal atlas of the Monodelphis opossum brain. It is based on four complementary imaging modalities: high resolution ex-vivo magnetic resonance images, micro-computed tomography scans of the cranium, images of the face of the cutting block, and series of sections stained with Nissl method and for myelinated fibers. Individual imaging modalities were reconstructed into a three-dimensional form and then registered to the MR image by means of affine and deformable registration routines. Based on a superimposition of the 3D images, 113 anatomical structures were demarcated and the volumes of individual regions were measured. The stereotaxic coordinate system was defined using a set of cranial landmarks: interaural line, bregma, and lambda, which allows for easy expression of any location within the brain with respect to the skull. 
    14   
    15  The atlas is released under the Creative Commons license and available through various digital atlasing web services.  
     13Here we present the first three-dimensional, multimodal atlas of the ''Monodelphis'' opossum brain. It is based on four complementary imaging modalities: high resolution ex-vivo magnetic resonance images, micro-computed tomography scans of the cranium, images of the face of the cutting block, and series of sections stained with Nissl method and for myelinated fibers. Individual imaging modalities were reconstructed into a three-dimensional form and then registered to the MR image by means of affine and deformable registration routines. Based on a superimposition of the 3D images, 113 anatomical structures were demarcated and the volumes of individual regions were measured. The stereotaxic coordinate system was defined using a set of cranial landmarks: interaural line, bregma, and lambda, which allows for easy expression of any location within the brain with respect to the skull. 
     14The atlas is released under the Creative Commons license and available through various digital atlasing web services. 
    1615 
    1716== The following supplementary materials are available: == 
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